Intravenous penicillin.

Intravenous Penicillin for Antenatal Syphilotherapy

A 21 year old woman (G(2) P(0101)) of 24 weeks gestation presented with syphilis of unknown duration. Sonography revealed fetal hydrops and placental thickening. Weekly intramuscular injections of 2.4 million U Bicillin for 3 weeks was initiated as recommended by the Centers for Disease Control. Repeat sonogram 1 week after starting treatment revealed increased ascites and a new pericardial eff...

Intramuscular versus intravenous administration of benzathine penicillin.

To the Editor—As a reader of Clinical Infectious Diseases living and working in Vietnam, I was naturally drawn to the article by Murray et al. [1] about infections during the Vietnam-America conflict. I was, however, disappointed to see the expression “the global war on terrorism” appear twice in the article. “The global war on terrorism” is a doctrinal slogan that may be popular in the United ...

Cardiac arrest due to hyperkalemia following intravenous penicillin administration.

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The Absorption and Excretion of Penicillin following Continuous Intravenous and Subcutaneous Administration.

Penicillin, a product of the growth of a fungus, penicillium notatum, has become established as a therapeutic agent of value in the management of various infections, particularly those caused by the pyogenic cocci (1). Because penicillin is unstable in the presence of acid, it may not be given by mouth and absorption from the duodenum is imperfect. It has, therefore, been administered parentera...